六氟化锇是一种黄色晶体，熔点为33.4 °C，沸点为47.5 °C。在−140 °C是测得它的固态结构为正交晶系晶体，空间群为Pnma。晶胞参数a = 9.387 Å，b = 8.543 Å，而c = 4.944 Å。每个晶胞中有四个化学式单位的六氟化锇（这里是四个六氟化锇分子），密度则是5.09 g·cm−3。
Osmium hexafluoride is a yellow crystal with a melting point of 33.4 ° C and a boiling point of 47.5 ° C. At − 140 ° C, its solid state structure is orthorhombic crystal, and its space group is Pnma. Cell parameters a = 9.387 μ m, B = 8.543 μ m, and C = 4.944 μ M. There are four chemical formula units of osmium hexafluoride in each cell (here are four osmium hexafluoride molecules), and the density is 5.09 g · cm − 3.